1. Radiographic features in infants are generally less severe than those seen in perinatal hypophosphatasia . 2. Similar illnesses : hypophosphatasia , juvenile osteoporosis. 3. Perinatal hypophosphatasia is the most lethal form. 4. Hypophosphatasia in childhood has variable clinical expression.5. In newborns, X-rays readily distinguish hypophosphatasia from osteogenesis imperfecta and congenital dwarfism. 6. Diseases causing soft bones in infants, like hypophosphatasia or hypophosphatemia can also lead to rickets. 7. Enobia is the developer of asfotase alpha, a drug used to treat the genetic disorder hypophosphatasia . 8. In infants, radiographic features of hypophosphatasia are striking, though generally less severe than those found in perinatal hypophosphatasia. 9. In infants, radiographic features of hypophosphatasia are striking, though generally less severe than those found in perinatal hypophosphatasia . 10. Infantile hypophosphatasia presents in the first 6 months of life, with the onset of poor feeding and inadequate weight gain.
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