Obesity in rats was significantly reduced by adrenalectomy or hypophysectomy.
2.
Houssay demonstrated in the 1930s the diabetogenic effect anterior hypophysis extracts and the decrease in diabetes severity with anterior hypophysectomy.
3.
Medications that are given as hormone replacement therapy following a complete hypophysectomy ( removal of the pituitary gland ) are often glucocorticoids.
4.
He worked on developing hypophysectomy with Harvey Cushing, and they and Samuel James Crowe published the first evidence of the link between the pituitary gland and the reproductive system in 1910.
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