These include revascularization and formation of granulation ( scar ) tissue, absorption of necrotic fragments, intertrabecular osteoid deposition, and remodeling of new bone.
2.
On the bone marrow biopsy, high grade dysplasia ( RAEB-I and RAEB-II ) may show atypical localization of immature precursors ( ALIPs ) which are islands of immature precursors cells ( myeloblasts and promyelocytes ) localized to the center of the intertrabecular space rather than adjacent to the trabeculae or surrounding arterioles.
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