1. Currently alternative methods for detection of this intrathecal synthesis have been published. 2. Certain treatments for childhood cancer are known to cause intrathecal chemotherapy ). 3. Both have since begun intrathecal treatments beginning in January 2012. 4. When concentrations are normalised for total IgG, intrathecal synthesis is detected. 5. Intrathecal MK-801 also blocked hyperalgesia resulting from continuous SP infusions.6. Intrathecal gabazine treatment before muscimol blocked the increase in phosphorylated NR1 expression.7. For example, intrathecal immunoglobulin production is production of antibodies in the spinal cord. 8. Before his invention patients had to suffer repeated lumbar punctures for intrathecal drug administration. 9. In combination, intrathecal chemotherapy most often comprises methotrexate, cytarabine, thiotepa and steroids. 10. These doses were an order of magnitude higher than is currently used for intrathecal delivery.
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