1. Alpha 2-antiplasmin and alpha 2-macroglobulin inactivate plasmin. 2. Alpha-2 macroglobulin may be elevated in children and the elderly. 3. Alpha-2-Macroglobulin is the largest major nonimmunoglobulin protein in plasma. 4. The alpha-macroglobulin ( aM ) receptors and be removed from circulation. 5. Increased production of all proteins means alpha-2-macroglobulin concentration increases. 6. Because of its size, alpha-2-macroglobulin is retained in the bloodstream. 7. The loss of alpha-2-macroglobulin into urine is prevented by its large size. 8. ApoER2 cDNA encoding proteins associated with A? was used to discover alpha-2-macroglobulin . 9. Alpha 2 macroglobulin acts as an antiprotease and is able to inactivate an enormous variety of proteinases. 10. Alpha-2-macroglobulin has in its structure a 35 amino acid " bait " region.