1. Each macromere has the potential of becoming the D macromere. 2. Each macromere has the potential of becoming the D macromere . 3. This larger cell is specified as the D macromere . 4. :Specification of the D macromere and is an important aspect of spiralian development. 5. This contact is required to distinguish one macromere as the official D quadrant blastomere. 6. The polar lobe contains vegetal cytoplasm, which becomes inherited by the future D macromere . 7. The D macromere facilitates cell divisions that differ from those produced by the other three macromeres. 8. At the 4-cell stage of equal cleavage, the D macromere has not been specified yet. 9. All teloblasts are specified from the D quadrant macromere after the second round of divisions post-fertilization. 10. Unlike equally cleaving spiralians, the D macromere is specified at the four-cell stage during unequal cleavage.