1. Excessive use or overdose causes constipation and can promote development of megacolon . 2. Toxic megacolon is the article you're looking for. 3. Acute megacolon can also lead to ischemic necrosis in massively dilated intestinal segments. 4. :: : : I once saw a photo of a preserved megacolon . 5. Acute megacolon develops because of abnormal intestinal motility. 6. A megacolon can be either chronic. 7. Toxic megacolon is usually a Clostridium difficile " infections, which have led to pseudomembranous colitis. 8. In cats, perineal hernias are seen most commonly following perineal urethrostomy surgery or secondary to megacolon . 9. CMV may also increase the risk of toxic megacolon in non-HIV / AIDS patients with IBD. 10. This mass may stretch the walls of the rectum and colon, causing megarectum and / or megacolon , respectively.