1. However, this article will discuss only metabolite -binding riboswitches. 2. Primary metabolite enzymatic cofactors include members of the vitamin B family. 3. It is sparingly metabolised in the liver to two inactive metabolites . 4. Cloxazolam is metabolised into the active metabolite chlordesmethyldiazepam ( delorazepam ). 5. In rats 52-hydroxypagoclone was identified as a major metabolite . 6. Befuraline's active metabolite benzylpiperazine is responsible for its effects. 7. Secondary metabolite production seems to have arisen quite early during evolution. 8. These alternate metabolites of COX-1 may contribute to its activities 9. It is a metabolite of testosterone and dihydrotestosterone ( DHT ). 10. The antihistamine agent terfenadine produces azacyclonol as an active major metabolite .