1. During development, the human DNA methylation profile experiences dramatic changes. 2. His test detects epigenetic modifications, in particular, DNA methylation . 3. Methylation , along with histone modification, is central to imprinting.4. The S subunit determines the specificity of both restriction and methylation . 5. DNA methylation may affect the transcription of genes in two ways. 6. Thioflavin S results from the methylation of dehydrothiotoluidine with sulfonic acid. 7. Many cancers arise from the inappropriate epigenetic effects of misregulated methylation . 8. This happens through the transsulfuration pathway and the methylation of homocysteine. 9. Some miRNAs also undergo methylation -associated silencing in cancer cells. 10. Also, aberrant methylation patterns are well characterized in many cancers.
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