1. Increased reactive oxygen, and nitrogen species are secreted by activated microglia . 2. Microglia are the main target of HIV-1 in the brain.3. The CCL2 chemokine is also expressed by neurons, astrocytes and microglia . 4. It destroys myelin either directly or indirectly through microglia activation. 5. The increased receptor expression causes microglia to become more active. 6. Among brain cells, the Iba1 gene was specifically expressed in microglia . 7. Stevens is exploring the role of microglia in disorders such as autism. 8. Activated microglia produced toxic substances that are also typically secreted in inflammatory reactions. 9. BDNF released from microglia induces neuronal hyperexcitability through interaction with the TrkB receptor. 10. Additionally, cannabinoids completely abolish neurotoxicity related to microglia activation in rat models.
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