1. Extracellular signals are transduced into cells through mitogen -activated protein kinases. 2. It is cAMP, calcium / calmodulin, mitogen , and cyclin. 3. P38 mitogen -activated protein kinases are mediators of inflammation. 4. It is a type of mitogen which is specific only to certain kinds of cells. 5. Activation also results in the activation of mitogen -activated protein kinases and Src kinase. 6. MAP2K1 is also known as MEK1 ( see Mitogen -activated protein kinase kinase ). 7. This kinase is known to play a critical role in mitogen growth factor signal transduction. 8. This cytokine regulates the activities of NF-kappaB and mitogen -activated protein kinases. 9. He named it lymphocyte-activating factor ( LAF ) because it was a lymphocyte mitogen . 10. An exception is the prosecretory mitogen lacritin that binds syndecan-1 only after heparanase modification.