In eukaryotes, lanosterol synthase is an integral monotopic protein associated with the cytosolic side of the endoplasmic reticulum.
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"' Integral monotopic proteins "', are permanently attached to the membrane from one side.
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The other type of integral membrane protein is the integral monotopic protein that is also permanently attached to the cell membrane but does not pass through it.
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The integral membrane proteins are classified as transmembrane proteins that span across the membrane and integral monotopic proteins that are attached to only one side of the membrane.
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