myoglobinuria sentence in Hindi
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- CPT II deficiency is also the most frequent cause of hereditary myoglobinuria.
- Cocaine-induced hyperthermia may cause muscle cell destruction and myoglobinuria resulting in renal failure.
- It has been referred to as " atypical myopathy " or " myoglobinuria of unknown etiology ".
- It is possible to use an ammonia sulphate precipitation test in order to distinguish between hemoglobinuria and myoglobinuria.
- As detectable levels of myoglobinemia and myoglobinuria occur, blood tests and urine tests may show elevated levels of myoglobin.
- Clinical laboratory changes include evidence of rhabdomyolysis ( elevated CK and AST, myoglobinuria ) and low blood selenium levels.
- Two colour charts are provided that correspond to the reactions that occur with hemoglobinuria, myoglobinuria and hematuria ( RBCs ).
- "' Myoglobinuria "'is the presence of myoglobin in the urine, usually associated with rhabdomyolysis or muscle destruction.
- Muscle tissue destruction can lead to myoglobinuria, with renal failure following in severe cases; this is similar to burns from electric current.
- The final form presents in adulthood, and presents as isolated skeletal muscle involvement, rhabdomyolysis, and myoglobinuria, which is triggered by exercise or fasting.
- Signs and symptoms of myoglobinuria are usually nonspecific and needs some clinical prudence . Therefore, among the possible signs and symptoms to look for would be:
- Patients with PGAM deficiency are usually asymptomatic, except when they engage in brief, strenuous efforts which may trigger myalgias, cramps, muscle necrosis and myoglobinuria.
- In the long term, patients may exhibit renal failure due to the myoglobinuria, and with age, patients may exhibit progressively increasing weakness and substantial muscle loss.
- Tarui disease is a glycogen storage disease with symptoms including muscle weakness ( myopathy ) and exercise induced cramping and spasms, myoglobinuria ( presence of myoglobin in urine, indicating muscle destruction ) and compensated hemolysis.
- Deficiency in PFK leads to glycogenosis type VII ( Tarui's disease ), an autosomal recessive disorder characterised by severe nausea, vomiting, muscle cramps and myoglobinuria in response to bursts of intense or vigorous exercise.
- Mutations of the M subunit have been linked to the rare disease " exertional myoglobinuria " ( see OMIM article ), and mutations of the H subunit have been described but do not appear to lead to disease.
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