1. People with the disease have higher than normal levels of osteoclasts . 2. The cause of the disease is understood to be malfunctioning osteoclasts . 3. The two types of bisphosphonates work differently in killing osteoclast cells. 4. The osteoclasts dissolve the part of the bone that must change. 5. Pepstatin A suppresses the formation of multinuclear osteoclasts dose-dependently. 6. MicroRNA-223 also plays an essential role during osteoclast differentiation. 7. Bone-eating cells called osteoclasts have long been implicated in osteoporosis. 8. And they may also speed the action of osteoclasts , Rosen said. 9. Siris said alendronate works by coating surplus osteoclasts and suppressing their action. 10. Calcitonin lowers blood calcium and phosphorus mainly through its inhibition of osteoclasts .
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