Often minor ductal and periductal inflammation is present.
2.
Duct widening with associated periductal fibrosis is frequently included in the wastebasket definition of fibrocystic disease.
3.
The duct ectasia periductal mastitis complex affects two groups of women : young women ( in their late teens and early 20s ) and perimenopausal women.
4.
Periductal mastitis, comedo mastitis, secretory disease of the breast, plasma cell mastitis and mastitis obliterans are sometimes considered special cases or synonyms of duct ectasia syndrome.
5.
In humans, the onset of cholangiocarcinoma occurs with chronic opisthorchiasis, associated with hepatobiliary damage, inflammation, periductal fibrosis and / or cellular responses to antigens from the infecting fluke.
6.
These parasites are long-lived and cause heavy chronic infections that may lead to accumulation of fluid in the legs ( edema ) and in the peritoneal cavity ( ascites ), enlarged non-functional gall-bladder and also cholangitis, which can lead to periductal fibrosis, cholecystitis and cholelithiasis, obstructive jaundice, hepatomegaly and / or fibrosis of the periportal system.
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