1. These include piperine , which gives black pepper its spicy taste. 2. The spiciness of black pepper is due to the chemical piperine . 3. It is one of the four diastereomeric geometric isomers of piperine . 4. Piperine remains the most potent and extensively researched bioenhancer till date.5. In animal studies, piperine inhibited CYP450 enzymes involved in drug metabolism. 6. Besides the antibiotics rifampicin and isoniazid it contains piperine . 7. One example investigated is the potential for piperine to enhance the bioavailability of curcumin. 8. Piperine is being studied for its potential to affect bioavailability of other compounds in food.9. Pepper gets its spicy heat mostly from piperine derived both from the outer fruit and the seed. 10. After the discovery of bioenhancer Piperine in 1979, a new chapter was added in medical science.
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