This species produces pregnane glycosides or cynanchosides.
2.
Also like progesterone, recent evidence has shown that allopregnanolone is an activator of the pregnane X receptor.
3.
All endogenous progestogens are characterized by their basic 21-carbon skeleton, called a pregnane skeleton ( C21 ).
4.
Hyperforin also induces cytochrome P450 enzymes CYP3A4 and CYP2C9 by binding to and activating the pregnane X receptor ( PXR ).
5.
These drugs prevent the conversion of pregnane steroids into androgens like testosterone and therefore are androgen biosynthesis inhibitors and functional antiandrogens.
6.
The gene expression of these isoenzymes is regulated by human pregnane receptor X ( PXR ) and constitutive androstane receptor ( CAR ).
7.
"' 17?-Hydroxypregnenolone "'is a pregnane ( C21 ) steroid that is obtained by hydroxylation of pregnenolone at the C17? position.
8.
It is a parent hydrocarbon for two series of steroids stemming from 5?-pregnane ( originally allopregnane ) and 5?-pregnane ( 17?-ethyletiocholane ).
9.
It is a parent hydrocarbon for two series of steroids stemming from 5?-pregnane ( originally allopregnane ) and 5?-pregnane ( 17?-ethyletiocholane ).
10.
5?-Pregnane is the parent of the progesterones, pregnane alcohols, ketones, and several adrenocortical hormones and is found largely in urine as a compounds.
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