When neuroendocrine cell hyperplasia and tumorlets are extensive, they represent the rare preinvasive lesion for carcinoids known as " diffuse idiopathic pulmonary neuroendocrine cell hyperplasia ".
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Now, however, at a time when preinvasive cervical abnormalities are occurring at epidemic levels, many women, especially those past menopause who do not get regular gynecological examinations, are failing to get annual Pap smears.
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Exceptions include CIS of the colon ( polyps ), the bladder ( preinvasive papillary cancer ), or the breast ( ductal carcinoma " in situ " or lobular carcinoma " in situ " ).
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