1. Xylazine is a superior premedication with ketamine resulting in safer recoveries. 2. Clonidine is becoming increasingly popular as a premedication for children. 3. One commonly used premedication is clonidine, an alpha-2 adrenergic agonist. 4. Melatonin premedication also reduces the required induction dose of propofol and sodium thiopental. 5. Sufentanil is also sometimes used as a premedication . 6. Delorazepam is also used as a premedication for dental phobia for its anxiolytic properties. 7. Melatonin in comparison to placebo is effective for reducing preoperative anxiety in adults when given as premedication . 8. Clonidine is also a mild sedative, and can be used as premedication before surgery or procedures. 9. Premedication with corticosteroids is recommended before each administration of docetaxel to reduce fluid retention and hypersensitive reactions.10. In children, clonidine premedication is at least as effective as benzodiazepines and has less serious side effects.
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