A 2012 review of the regulatory status of DMAA found that " 1, 3-Dimethylamylamine ( DMAA ) is a pressor amine often found in food supplements for athletes at dosages of 25-65 mg.
No significant rise in blood pressure occurs when moclobemide is combined with amines such as tyramine-containing foods or pressor amine drugs, unlike with the older nonselective and irreversible monoamine oxidase inhibitors ( MAOIs ), which cause a severe rise in blood pressure with such combination.
Its only current clinical use is in preparing patients with phaeochromocytoma for surgery; its irreversible antagonism and the resultant depression in the maximum of the agonist dose-response curve are desirable in a situation where surgical manipulation of the tumour may release a large bolus of pressor amine into the circulation.
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