Owren initially felt that factor V ( labile factor or proaccelerin ) activated another factor, which he named VI . VI was the factor that accelerated the conversion from prothrombin to thrombin.
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A first clue as to the actual complexity of the system of coagulation was the discovery of " proaccelerin " ( initially and later called Factor V ) by Paul Owren ( 1905 1990 ) in 1947.
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