About 10 percent of healthy individuals show excess radiosensitivity in the cell test.
2.
A rare polymorphism in this gene is associated with cancer in patients of varying radiosensitivity.
3.
A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity.
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It may also function in the suppression of radiosensitivity since it is associated with ataxia telangiectasia phenotype.
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The next step will be to investigate the extent to which radiosensitivity is inherited, by studying twins.
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A more immediately useful idea is to test patients'radiosensitivity as soon as cancer has been diagnosed.
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If the tests are successful, the assay could be used to assess the radiosensitivity of tumors elsewhere in the body.
8.
A third technique is to enhance the radiosensitivity of the cancer by giving certain drugs during a course of radiation therapy.
9.
This protein interacts with DNA ligase III, polymorphism in this gene is associated with cancer in patients of varying radiosensitivity.
10.
Moreover, the cytoprotective effects of this protein can promote tumor cell survival in radiotherapy treatments, while silencing its gene increases radiosensitivity.
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