The SLX1-SLX4 complex acts as a Holliday junction resolvase.
2.
This pathway includes the Mus81 resolvase and the Sgs1 helicase.
3.
RuvC is the resolvase, which cleaves the Holliday junction.
4.
The CX3 complex associates with Holliday junction resolvase activity, probably in a role of stabilizing gene conversion tracts.
5.
The CX3 complex was shown to associate with Holliday junction resolvase activity, probably in a role of stabilizing gene conversion tracts.
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Hyperactive resolvase mutants, if further developed, could become an alternative to FLP, the most commonly used recombination systems in molecular biology to date.
7.
RHAU exhibits a unique ATP-dependent guanine-quadruplex ( G4 ) resolvase activity and specificity for its substrate " in vitro ".
8.
The functions of several of these proteins is known : these include the terminase, endonuclease, exonuclease, resolvase, helicase, primase and single-stranded binding protein.
9.
The converse examples are PhiC31 and related SRs, which were originally introduced as resolvase / invertases although, in the absence of auxiliary factors, integration is their only function.
10.
The entire resolvase recombination reaction can be reproduced " in vitro ", requiring only resolvase, a substrate DNA and multivalent cations, using either wild type protein or hyperactive mutants.
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