11. Mutations in " MUT " gene may lead to various types of methylmalonic aciduria . 12. In peroxisomes, the accumulation of this substance causes malonic aciduria , a highly pathogenic disease. 13. Urocanic aciduria is thought to be relatively benign . no definitive neurometabolic connection has yet been established. 14. The metabolic disease was found to be on a unsaturated dicarboxylic acids, a condition called dicarboxylic aciduria . 15. The incidence of 3-methylglutaconic aciduria type II is approximately 1 in 200, 000 male infants. 16. Uridine triacetate is a drug approved by FDA to be used in the treatment of hereditary orotic aciduria . 17. Glutaric aciduria type 1, in many cases, can be defined as a cerebral palsy of genetic origins. 18. Mutations in the L2HGDH gene cause L-2-hydroxyglutaric aciduria , a rare autosomal recessive neurometabolic disorder. 19. Mutations in IDH2 are associated with 2-hydroxyglutaric aciduria , a condition that causes progressive damage to the brain. 20. Mutations in the gene are the cause of vitamin B 12-dependent methylmalonic aciduria linked to the cblB complementation group.