11. Entrance into anaphase is mediated by APCCdc20 activation. 12. Hair follicles in anaphase express four different caspases. 13. Plk phosphorylates and activates components of the anaphase -promoting complex ( APC ). 14. However, the most important interaction of Cdc20 is with the Anaphase Promoting Complex. 15. However, the role of TTC39C in anaphase must be confirmed through additional studies. 16. During mitotic progression, typically after the anaphase onset, the cell may undergo cytokinesis. 17. In its active state it is part of the checkpoint that blocks transition to anaphase . 18. Separase is vital for onset of anaphase . 19. To initiate the onset of anaphase , securin is dephosphorylated by Cdc14 and other phosphatases. 20. Switch-like characteristics are necessary to trigger quick, coordinated chromosomal segregation in anaphase .