Other active ingredients include farnesene, chamazulene, flavonoids ( including apigenin, quercetin, patuletin and luteolin ) and coumarin.
12.
Apigenin is a potent inhibitor of CYP2C9, an enzyme responsible for the metabolism of many pharmaceutical drugs in the body.
13.
After this step, it is proposed that flavonoid 3 5-hydroxylase ( F3 5 H ) changes apigenin into tricetin.
14.
Though a 1994 study shows it contains apigenin, an anti-anxiety agent, it's weaker than valerian and kava.
15.
Apigenin induces autophagy ( a kind of cellular waste-recycling system ) in leukemia cells, which may support a possible chemopreventive role.
16.
Therefore, transforming growth factor-? and apoptotic index may be used to assess apigenin and its effect on ciclosporin-induced renal damage.
17.
Desert broom also has quercetin, a proven antioxidant, and apigenin a chemical which binds to the same brain receptor sites that Valium does.
18.
Non-specific inhibitors ( apigenin, sulfated glycosaminoglycans ) or crude enzyme extracts have been used to test most hypotheses, making data difficult to interpret.
19.
Apigenin has been shown to prevent renal damage caused by ciclosporin in rats, associated with reduced expression of the cell death mediator bcl-2 in histopathological sections.
20.
Antiinflammatory effect Several chemical constituents of chamomile such as bisabolol, chamazulene, apigenin, and luteolin possess anti-inflammatory properties although the exact mechanism is not well characterized.
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