The ensuing inflammation leads to formation of atheromatous plaques in the arterial tunica intima, a region of the vessel wall located between the endothelium and the tunica media.
12.
Kaartinen M, Penttila A, Kovanen PT . Accumulation of activated mast cells in the shoulder region of human coronary atheroma, the prediction site of atheromatous rupture.
13.
This was based on Constantinides s observation that circulating mast cell precursors could penetrate the open junctions between endothelial cells that line human atheromatous plaques in contrast to closed junctions over the normal arterial intima.
14.
The buildup of an atheromatous plaque is a slow process, developed over a period of several years through a complex series of cellular events occurring within the arterial wall and in response to a variety of local vascular circulating factors.
15.
While many of these products are used as markers of oxidative stress, the products derived from linoleic acid appear far more predominant than arachidonic acid products and therefore easier to identify and quantify in, for example, atheromatous plaques.
16.
Type II variant : includes patients with culprit but quiescent pre-existing atheromatous disease in whom the acute release of inflammatory mediators can induce either coronary artery spasm with normal cardiac enzymes and troponins or plaque erosion or rupture manifesting as acute myocardial infarction
17.
Instead it was simply a remodeling of the atheromatous plaque, which was still protruding into the lumen of the artery after completion of angioplasty; the stenosis only appearing to be reduced because blood and contrast could now flow around and through some of the plaque.
18.
The calcification deposits, after they have become sufficiently advanced, are partially visible on coronary artery computed tomography or electron beam tomography ( EBT ) as rings of increased radiographic density, forming halos around the outer edges of the atheromatous plaques, within the artery wall.
19.
The ( a ) blood vessel wall inner lining, ( b ) atheromatous disease within the wall and ( c ) connective tissues covering the outer surface of the blood vessel are echogenic, i . e . they return echoes making them visible on the ultrasound display.
20.
Additionally, IVUS examinations, as they were done more frequently, served to reveal and confirm the autopsy research findings of the late 1980s, showing that atheromatous plaque tends to cause expansion of the internal elastic lamina, causing the degree of plaque burden to be greatly underestimated by angiography.
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