More than a million US women take alendronate, up from 810, 000 in July, a Merck spokeswoman said.
22.
Alendronate is known to cause digestive problems in some, but few were seen in these studies at the doses used.
23.
Although some doctors have prescribed alendronate for children with osteogenesis imperfecta, the Shriners investigators haven't outside the trial.
24.
Recent studies have reported bisphosphonate use ( specifically zoledronate and alendronate ) as a risk factor for atrial fibrillation in women.
25.
Some of these drugs, like alendronate, are part of a class known as biphosphanates that inhibit the breakdown of bone.
26.
Fosamax, known chemically as alendronate, is being evaluated at 14 Shriners Hospitals for Children in the United States and Canada.
27.
The number of patients on alendronate suffering spinal fractures was about half the number taking a placebo who suffered them, the studies showed.
28.
It was hypothesized that part of the reason that treatment with an FTI such as alendronate is inefficient is due to prenylation by geranylgeranyltransferase.
29.
Among women receiving alendronate, 11 suffered hip fractures over the three-year study period, compared to 22 among women receiving a placebo.
30.
Merck filed a U . S . Food and Drug Administration application in March seeking approval for Fosamax, whose chemical name is alendronate sodium.
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