:That's pretty much the way Disulfiram ( Antabuse ) works in the treatment of chronic alcoholism.
22.
Pharmacological treatments for alcohol addiction include drugs like naltrexone ( opioid antagonist ), disulfiram, acamprosate, and topiramate.
23.
Disulfiram ( also called Antabuse ) produces a very unpleasant reaction when drinking alcohol that includes flushing, nausea and palpitations.
24.
In addition, TNX-301 ( disulfiram 250 mg / selegiline 4 mg tablets ), is in preclinical development.
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The drug disulfiram ( Antabuse ) prevents the oxidation of acetaldehyde to acetic acid and is used in the treatment of alcoholism.
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Several drugs ( e . g ., metronidazole ) cause a similar reaction known as " disulfiram-like reaction ."
27.
The other drug, disulfiram, discourages drinking by causing nausea, vomiting and other symptoms of a hangover if a person drinks.
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As it is formed in the liver after ethanol ingestion or disulfiram treatment, it is also associated with the study of alcoholism.
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Metronidazole ( Flagyl ), which is used to treat certain parasitic infections as well as pseudomembranous colitis, causes similar effects to disulfiram.
30.
A more unusual toxin is coprine, a disulfiram-like compound that is harmless unless ingested within a few days of ingesting alcohol.
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