The enzyme hexokinase phosphorylates a six-carbon sugar, most notably glucose, which is the first step in glycolysis.
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Glucokinase ( GK ) is a hexokinase isozyme, related kinetic properties allow it to serve a different set of functions.
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Some other examples of enzymes are phosphofructokinase and hexokinase, both of which are important for cellular respiration ( glycolysis ).
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Glucose-1, 6-bisphosphate inhibit hexokinase stopping the production glucose-6-phosphate from D-glucose.
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More precise blood glucose measurements are performed in a medical laboratory, using hexokinase, glucose oxidase, or glucose dehydrogenase enzymes.
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The product s inhibition of hexokinase and activation of PFK-1 and pyruvate kinase is indicative of its role in glycolysis.
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"' Hexokinase "'is the most common enzyme that makes use of glucose when it first enters the cell.
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During World War II he worked on government-assigned crystallization projects and was noted for the facility with which he crystallized hexokinase.
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In glycolysis, hexokinase is directly inhibited by its product, glucose-6-phosphate, and pyruvate kinase is inhibited by ATP itself.
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In addition hexokinase and glucokinase act independently of the hormonal effects as controls at the entry points of glucose into the cells of different tissues.
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