21. It must first undergo metabolic l'- hydroxylation in the liver before achieving toxicity. 22. In fact, hydroxylation is sometimes followed by dehydrogenation, leading to more complex metabolites. 23. The metabolic pathways : benzoate degradation via hydroxylation , carbazole degradation, and nitrogen metabolism. 24. This enzyme participates in benzoate degradation via hydroxylation and c5-branched dibasic acid metabolism. 25. The bicyclic decalin ring system is formed via the eudesmyl cation followed by hydroxylation at C1. 26. Hydroxylation the occurs ortho to the nitroso group due to the directing effect of the metal.27. In its synthesis in the liver, 12? hydroxylation is performed by the additional action of CYP8B1. 28. Hydroxylation of any of these compounds followed by dehydration can lead to the aromatic p-cymene.29. The enzyme catalyzes the hydroxylation of Calcifediol to calcitriol ( the bioactive form of Vitamin D ): 30. The metabolic pathways : benzoate degradation via hydroxylation , toluene and xylene degradation, and fluorene degradation.
