Bernt Krebs was able to develop a number of highly interesting new compounds with promising properties, e . g ., without nephrotoxic side effects.
22.
Polymixin B prevents endotoxin from binding to inflammatory cells, but is potentially nephrotoxic, so should be used with caution in horses with azotemia, especially neonatal foals.
23.
However, this is not always an option; in such a situation, alternative drug therapy may be employed, if possible, to avoid this deleterious nephrotoxic.
24.
The obsolete ( as an anaesthetic ) agent methoxyflurane had a nephrotoxic effect and caused acute renal failure, usually attributed to the liberation of fluoride ions from its metabolism.
25.
Patients with kidney loss should be monitored for hypertension ( and treated for it if discovered ) and avoid nephrotoxic drugs such as certain pain relievers and IV contrast agents.
26.
Imipenem is hydrolyzed in the mammalian kidney by a dehydropeptidase enzyme to a nephrotoxic intermediate, and thus is co-formulated with the dehydropeptidase inhibitor cilastatin . and intramuscular formulations.
27.
Among the accidental causes of renal failure is the crush syndrome, when large amounts of toxins are suddenly released in the blood circulation after a long compressed nephrotoxic metabolites of myoglobin.
28.
"' Aristolochic acids "'( ) are a family of carcinogenic, mutagenic, and nephrotoxic compounds commonly found in the birthwort ( Aristolochiaceae ) family of plants.
29.
In short, it is nephrotoxic, neurotoxic, increases the risk of squamous cell carcinoma and infections, and often causes hypertension ( due to renal vasoconstriction and increased sodium reabsorption ).
30.
Both species caused renal damage only, the changes of which corresponded to tubulo-interstitial nephritis . " C . gentilis " has been found to be nephrotoxic to rats.
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