As might be expected of an enzyme involved in regulating NO levels and signaling, pleiotropic effects are observed in GSNOR knockout models.
22.
Interleukin 13 ( IL-13 ) is a pleiotropic cytokine that may be important in the regulation of the inflammatory and immune responses.
23.
Because the receptor gene is expressed in several forms, it has many different ( pleiotropic ) effects in different parts of the body.
24.
Interleukin 6 ( IL6 ) is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in immune response.
25.
Inhibition of IMPA1 activity can have pleiotropic effects on cellular function, including altering phosphoinositide signalling, autophagy, apoptosis, and other effects.
26.
"K " n also has other pleiotropic effects, as a reduction in comb size and hypertrophy of the uropygial gland.
27.
GCs have many diverse ( pleiotropic ) effects, including potentially harmful side effects, and as a result are rarely sold over the counter.
28.
Mice lacking functional copies of all three family members display pleiotropic phenotypes including exencephaly, edema, failures in neurite formation, and embryonic lethality.
29.
This autophosphorylation leads to phosphorylation of cytosolic targets as well as association with other molecules, which are involved in pleiotropic effects of signal transduction.
30.
If an ancestral gene is pleiotropic and performs two functions, often neither one of these two functions can be changed without affecting the other function.
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