21. Because the mutated SDH enzyme cannot convert succinate to fumarate, succinate accumulates in the cell. 22. The " gab " genes upon activation produce enzymes that degrade GABA to succinate . 23. The tartrate is an immediate-release formulation and the succinate is an extended-release formulation. 24. Succinate dehydrogenase is an important enzyme in both the citric acid cycle and the electron transport chain.25. Succinate generated in the first step can enter into the citric acid cycle to eventually form oxaloacetate.26. Isocitrate lyase ( ) is an enzyme that catalyzes the conversion of isocitrate to succinate and glyoxylate. 27. It can also utilize acetate, citrate, formate, lactate, and succinate as carbon sources. 28. Succinyl-CoA synthetase catalyzes the reversible reaction involving the formation of succinyl-CoA and succinate . 29. This conversion is catalysed by the enzyme succinate dehydrogenase ( or complex II of the mitochondrial ETC ). 30. In the glyoxylate cycle of plants and some prokaryotes, isocitrate lyase produces glyoxylate and succinate from isocitrate.
