Insertion is often painful; an anesthetic such as lidocaine can be used to make the insertion more tolerable and to help prevent vasospasm, thereby making insertion of the arterial line somewhat easier.
22.
The use of calcium channel blockers, thought to be able to prevent the spasm of blood vessels by preventing calcium from entering smooth muscle cells, has been proposed for the prevention of vasospasm.
23.
Similarly, sarcK ATP regulates vascular smooth muscle tone, and deletion of the " kir6.2 " or " sur2 " genes leads to coronary artery vasospasm and death.
24.
In 1983, the Russian neurosurgeon Zubkov and colleagues reported the first use of transluminal balloon angioplasty for vasospasm after aneurysmal SAH . The Italian neurosurgeon Dr Guido Guglielmi introduced his endovascular coil treatment in 1991.
25.
Other types of vascular complications include vasospasm, in which blood vessels constrict and restrict blood flow, and the formation of aneurysms, in which the side of a blood vessel weakens and balloons out.
26.
Some older studies have suggested that statin therapy might reduce vasospasm, but a subsequent meta-analysis including three further trials did not demonstrate evidence for benefit of statin use on either vasospasm or clinical outcomes.
27.
Some older studies have suggested that statin therapy might reduce vasospasm, but a subsequent meta-analysis including three further trials did not demonstrate evidence for benefit of statin use on either vasospasm or clinical outcomes.
28.
While ICAM-1 has not been shown to be directly correlated with cerebral vasospasm, a secondary symptom that affects 70 % of SAH patients, treatment with anti-ICAM-1 reduced the severity of vasospasm.
29.
While ICAM-1 has not been shown to be directly correlated with cerebral vasospasm, a secondary symptom that affects 70 % of SAH patients, treatment with anti-ICAM-1 reduced the severity of vasospasm.
30.
Some people with chest pain have normal or minimal narrowing of heart arteries; in these patients, vasospasm is a more likely cause for the pain, sometimes in the context of Prinzmetal's angina and syndrome X.
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