Mechanistically, promoter escape occurs through DNA scrunching, providing the energy needed to break interactions between RNA polymerase holoenzyme and the promoter.
32.
Mechanistically, acetylating Lys304 sterically hinders the NADP + from entering the NADP + structural site, which reduces the stability of the enzyme.
33.
Mechanistically, the human homolog is a scaffold protein linked to cellular differentiation centered on the regulation of epithelial as well as neuronal morphogenesis.
34.
Also cIAP1 and cIAP2 have been shown to bind caspases, although how the IAPs inhibit apoptosis mechanistically at the molecular level is not completely understood.
35.
This series of steps is mechanistically identical to the first half of the mechanism formation of the more well-known aryl and alkyl diazonium salts.
36.
Mechanistically, the effect of snowball Earth ( in particular the later glaciations ) on complex life is likely to have occurred through the process of kin selection.
37.
Trimming of 3 single-stranded tail is also needed in a mechanistically distinct subpathway of non-homologous end-joining, dependent on the Ku proteins.
38.
It is mechanistically distinct from multidrug resistance : It is not caused by mutant microbes, but rather by microbial cells that exist in a transient, parasites.
39.
These developments include two mechanistically distinct methods of triggering the cells inherent DNA repair mechanisms which are required to insert a foreign gene sequence into a live cell.
40.
Mechanistically, the reaction proceeds with potassium hydroxide deprotonating a methyl group and the resulting carbanion undergoing nucleophilic substitution with methyl iodide to form a new carbon carbon bond.
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