In studies on guinea pig trachea, Jordan and co-workers also found that synephrine had negligible activity on ? 1 and ? 2 receptors, being about 40000x less potent than norepinephrine.
32.
If you prefer a nasal spray for your stuffy nose, Afrin, Dristan or Neo-Synephrine are high on their list of drugs to help you breathe easier without raising your blood pressure.
33.
The above structural relationships all involve a change at " one " position in the synephrine molecule, and numerous other similar changes, many of which have been explored, are possible.
34.
Furthermore, " synephrine " exists as either of two enantiomers, while " ephedrine " exists as one of four different enantiomers; there are, in addition, racemic mixtures of these enantiomers.
35.
Mixtures containing synephrine as only one of their chemical components ( regardless of whether these are of synthetic or natural origin ) should not be assumed to produce exactly the same biological effects as synephrine alone.
36.
Mixtures containing synephrine as only one of their chemical components ( regardless of whether these are of synthetic or natural origin ) should not be assumed to produce exactly the same biological effects as synephrine alone.
37.
Qualitatively similar results were obtained in a rabbit ear preparation : 25 mg l-synephrine produced significant ( 50 % ) vasoconstriction, while the same concentration of d-synephrine elicited essentially no response.
38.
Qualitatively similar results were obtained in a rabbit ear preparation : 25 mg l-synephrine produced significant ( 50 % ) vasoconstriction, while the same concentration of d-synephrine elicited essentially no response.
39.
There was also one cannabinoid pill containing SGT-42 ( CUMYL-THPINACA ), and several " party pill " products containing mixtures of ingredients such as caffeine, hordenine, synephrine and kava.
40.
But some scientists note that synephrine can increase blood pressure and constrict blood vessels, as ephedra does, and question whether using it with caffeine could worsen those effects the way taking ephedra with caffeine does.
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