1. Some well-known decongestants are Afrin, Dristan, Neo-synephrine and Vicks Inhaler. 2. Soak some cotton in Afrin or Neo-Synephrine and place it into the bleeding nostril. 3. In physical appearance, synephrine is a colorless, crystalline solid and is water-soluble. 4. Racemic synephrine has been resolved using ammonium 3-bromo-camphor-8-sulfonate. 5. Over the counter : Afrin, Neo-Synephrine ; saline sprays include Ocean, Sea Mist. 6. No antagonism of norepinephrine was produced by concentrations of l-synephrine up to 10 " 5 M. 7. Bitter orange is also employed in herbal medicine as a stimulant and appetite suppressant, due to its active ingredient, synephrine . 8. The main differences of the synephrine isomers compared for example to the ephedrines are the hydroxy-substitutions on the benzene ring. 9. The i . m . administration of 75 500 mg of synephrine did not relieve acute asthma attacks, contradicting an earlier claim. 10. Synephrine behaved as a partial agonist at ? 1A receptors, but as an antagonist at ? 2A and ? 2C sub-types.