41. The endothelium regulates local vascular tone and integrity through the coordinated release of vasoactive molecules. 42. The endothelium is a single cell layer that separates the cornea from the aqueous humor. 43. Instead, they will begin to express markers that are specific to blood vessel endothelium . 44. In physiology research, sodium nitroprusside is frequently used to test endothelium -independent vasodilation. 45. First, platelets attach to substances outside the interrupted endothelium : " adhesion ". 46. The endothelium also produces molecules that discourage the blood from clotting unless there is a leak. 47. Variations in the flow of blood that circulates by arterioles are capable of responses in endothelium . 48. The canal is essentially an endothelium -lined tube, resembling that of a lymphatic vessel. 49. This channel which is activated by ATP depletion is found on neurons, neuroglia and endothelium . 50. They also inhibit mast cell activation, and leukocyte and platelet adherence to the vascular endothelium .