41. Human and yeast glutathione synthetases are ?-glutamylcysteine. 42. Glutathione synthetase is important for a variety of biological functions in multiple organisms.43. We related this inhibitory activity to a selective depletion of intracellular glutathione synthesis. 44. NWPI can raise glutathione levels and reduce oxidative stress. 45. Glutaredoxins are oxidized by substrates, and reduced non-enzymatically by glutathione . 46. Cysteine is the substrate in the synthetic pathway for glutathione in the eye. 47. This enzyme participates in cysteine metabolism and glutathione metabolism. 48. This enzyme participates in methionine metabolism and glutathione metabolism. 49. Numerous inhibitors have been developed, most of which share the glutathione moiety. 50. This gene encodes a glutathione S-transferase belonging to the alpha class.
