1. There are at least four different glutathione peroxidase isozymes in animals. 2. L-cysteine is a precursor to the biologic antioxidant glutathione . 3. APX is an integral component of the glutathione -ascorbate cycle. 4. This protein is remotely related to microsomal glutathione S-transferase. 5. Their activity is attributed to their mimicry of glutathione peroxidase activity. 6. Glutathione has antioxidant properties since the thiol group in its cysteine Kinetoplastids.7. Selenium enzymes are involved in the small reducing molecules glutathione and thioredoxin. 8. At usual doses, NAPQI is quickly detoxified by conjugation with glutathione . 9. The glutathione peroxidase family consists of 8 known human isoforms. 10. However, glutathione peroxidase 4 knockout mice die during early embryonic development.
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