supercoiling sentence in Hindi
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- Negative supercoiling is also thought to favour the transition between B-DNA and Z-DNA, and moderate the interactions of DNA binding proteins involved in gene regulation.
- DNA gyrase was incubated with the MurI enzyme and then added to a sample of DNA; the results of this experiment showed inhibition of supercoiling activity when MurI was present.
- In supercoiling assays, coiled DNA is separated in the first dimension and denatured by a DNA intercalator ( such as ethidium bromide or the less carcinogenic chloroquine ) in the second.
- "' DNA supercoiling "'refers to the over-or under-winding of a DNA strand, and is an expression of the strain on that strand.
- Supercoiling plays an important part in polymerase activity because of the unwinding and rewinding of DNA . Because regions of DNA in front of RNAP are unwound, there are compensatory positive supercoils.
- Topoisomerases introduce both single-and double-strand breaks in the course of changing the DNA's state of supercoiling, which is especially common in regions near an open replication fork.
- Supercoiling is important in a number of biological processes, such as compacting DNA, and by regulating access to the genetic code, DNA supercoiling strongly affects DNA metabolism and possibly gene expression.
- Supercoiling is important in a number of biological processes, such as compacting DNA, and by regulating access to the genetic code, DNA supercoiling strongly affects DNA metabolism and possibly gene expression.
- Octameric protein complexes called nucleosomes are responsible for the amount of supercoiling of DNA, and these complexes can be temporarily modified by processes such as phosphorylation or more permanently modified by processes such as methylation.
- "' Jerome Vinograd "'( February 9, 1913 July 7, 1976 ) was an American biochemist who developed density gradient ultracentrifugation and contributed to the understanding of DNA supercoiling.
- The gyrase inhibition occurs in both supercoiling and relaxing activities of the DNA gyrase, and the study concluded that the inhibition activity was able to proceed, unchanged, in the presence of the racemase substrate.
- It is an important object of study in knot theory, algebraic topology, and differential geometry, and has numerous applications in mathematics and science, including quantum mechanics, electromagnetism, and the study of DNA supercoiling.
- In eukaryotes, DNA supercoiling exists on many levels of both plectonemic and solenoidal supercoils, with the solenoidal supercoiling proving most effective in compacting the DNA . Solenoidal supercoiling is achieved with histones to form a 10 nm fiber.
- In eukaryotes, DNA supercoiling exists on many levels of both plectonemic and solenoidal supercoils, with the solenoidal supercoiling proving most effective in compacting the DNA . Solenoidal supercoiling is achieved with histones to form a 10 nm fiber.
- In eukaryotes, DNA supercoiling exists on many levels of both plectonemic and solenoidal supercoils, with the solenoidal supercoiling proving most effective in compacting the DNA . Solenoidal supercoiling is achieved with histones to form a 10 nm fiber.
- SR proteins can become hypophosphorylated during elongation decreasing their affinity for RNA polymerase II causing SR proteins to move to Topo I . When Topo I complexes with SF2 / ASF, it can no longer undo the supercoiling of DNA causing elongation to pause.
- These proteins include helicases, which unwind the double-stranded DNA molecule to facilitate access to it, RNA polymerases, which bind to the DNA promoter to synthesize the growing RNA molecule, topoisomerases, which change the amount of supercoiling in DNA, helping it wind and unwind, as well as a large variety of transcription factors that regulate expression.
- SR proteins can also stabilize DNA during transcription through an interaction with Topoisomerase I . When Topoisomerase I, Topo I, reduces supercoiling caused by transcription when it is bound to DNA . When Topo I is not bound to DNA it can phosphorylate the SR protein SF2 / ASF . Topo I and SF2 / ASF interact when SF2 / ASF is hypophosphorylated during transcription elongation.
- There are, of course, a great many little oddities that you could mention in regard to it-artificial nanoscale engineering of complex structures, sequence-specific reception of radio-frequency or terahertz signals, the ability of supercoiling to convert overall torsion of the structure into a separation of strands, or vice versa, the ability to nick the structure so that topoisomerase I can release said supercoiling, under control, the ability of PCNA and other proteins to clamp onto the strand and run it like a more or less smooth " string " through holes in a protein complex . . . there must be thousands of specific relevant significances . talk ) 03 : 40, 26 August 2012 ( UTC)
- There are, of course, a great many little oddities that you could mention in regard to it-artificial nanoscale engineering of complex structures, sequence-specific reception of radio-frequency or terahertz signals, the ability of supercoiling to convert overall torsion of the structure into a separation of strands, or vice versa, the ability to nick the structure so that topoisomerase I can release said supercoiling, under control, the ability of PCNA and other proteins to clamp onto the strand and run it like a more or less smooth " string " through holes in a protein complex . . . there must be thousands of specific relevant significances . talk ) 03 : 40, 26 August 2012 ( UTC)
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