thyroglobulin sentence in Hindi
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- Each thyroglobulin molecule contains approximately 100-120 tyrosine residues, a small number of which ( < 20 ) are subject to iodination catalysed by thyroperoxidase.
- Hence, thyroglobulin levels in the blood are mainly used as a tumor marker for certain kinds of thyroid cancer ( particularly papillary or follicular thyroid cancer ).
- IL-10 produced by T regulatory cells was important in suppressing the mouse thyroglobulin specific T cell response and therefore protecting against Experimental autoimmune thyroiditis in mice.
- The protein is a precursor of the thyroid hormones; these are produced when thyroglobulin's tyrosine residues are combined with iodine and the protein is subsequently cleaved.
- Thyroglobulin will also be measurable in a healthy thyroid, and will increase with inflammation, and may also be used to measure the success of thyroid removal or ablation.
- Mouse models of autoimmune thyroiditis showed that a semi-mature phenotype of dendritic cells is maintained after mouse thyroglobulin immunization in GM-CSF treated but not control mice.
- Genes that are believed to be involved include those for thyroglobulin, thyrotropin receptor, protein tyrosine phosphatase nonreceptor type 22 and cytotoxic T-lymphocyte associated antigen 4 among others.
- Each thyroglobulin molecule contains approximately 100-120 tyrosine residues, but only a small number ( 20 ) of these are subject to iodination by thyroperoxidase in the follicular colloid.
- Finally, office based thyroid blood hormone studies, such as T4, T3, TSH, TPO thyroid antibodies, and cancer markers thyroglobulin, TG and Calcitonin, CT.
- It is produced as the precursor thyroglobulin ( this is " not " the same as TBG ), which is cleaved by enzymes to produce active T 4.
- This gene is a member of the Insulin-like growth factor-binding protein ( IGFBP ) family and encodes a protein with an IGFBP domain and a type-I thyroglobulin domain.
- Small globules of the follicular colloid ( Tg ) are endocytosed ( hormone ( TSH )-mediated ) and proteases in lysosomes digest iodinated thyroglobulin, releasing T3 and T4 within the thyrocyte cytoplasm.
- Caution, however, should be exercised in interpreting thyroglobulin results without thyroglobulin antibodies, since thyroglobulin antibodies commonly interfere in thyroglobulin immunoassays causing false positive and negative results which may lead to clinical misdirection.
- Caution, however, should be exercised in interpreting thyroglobulin results without thyroglobulin antibodies, since thyroglobulin antibodies commonly interfere in thyroglobulin immunoassays causing false positive and negative results which may lead to clinical misdirection.
- Caution, however, should be exercised in interpreting thyroglobulin results without thyroglobulin antibodies, since thyroglobulin antibodies commonly interfere in thyroglobulin immunoassays causing false positive and negative results which may lead to clinical misdirection.
- Caution, however, should be exercised in interpreting thyroglobulin results without thyroglobulin antibodies, since thyroglobulin antibodies commonly interfere in thyroglobulin immunoassays causing false positive and negative results which may lead to clinical misdirection.
- Under the guidance of Antoine Lacassagne, Leblond injected radioiodine-128, into a rat and found that the label promptly accumulated in the thyroid gland, presumably incorporated into the thyroid hormone precursor thyroglobulin.
- In 1956, together with Deborah Doniach and Peter Campbell, he made the classic discovery of thyroglobulin autoantibodies in Hashimoto's thyroiditis which helped to open the whole concept of a relationship between autoimmunity and human disease.
- EpCAM consists of an extracellular domain ( 242 amino acids ) with epidermal growth factor ( EGF )-and thyroglobulin repeat-like domains, a single transmembrane domain ( 23 amino acids ), and a short intracellular domain ( 26 amino acids ).
- Other bioactive RiPPs include the antibiotics cyclothiazomycin and bottromycin, the ultra-narrow spectrum antibiotic plantazolicin, and the cytotoxin patellamide A . Streptolysin S, the toxic virulence factor of " Streptococcus pyogenes ", is also a RiPP . Additionally, human thyroid hormone itself is a RiPP due to its biosynthetic origin as thyroglobulin.
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