uroporphyrinogen sentence in Hindi
Sentences
Mobile
- Therefore, alcohol consumption may increase the production of uroporphyrinogen, exacerbating symptoms in individuals with porphyria cutanea tarda.
- This enzyme is responsible for catalyzing the conversion of uroporphyrinogen to coproporphyrinogen through the removal of four carboxymethyl side chains.
- This is an autosomal recessive inborn error of metabolism that results from the markedly deficient activity of uroporphyrinogen III synthase.
- Additionally, exposure to chlorinated cyclic hydrocarbons can lead to a deficiency in the activity of uroporphyrinogen decarboxylase, causing the buildup of excess uroporphyrinogen.
- Additionally, exposure to chlorinated cyclic hydrocarbons can lead to a deficiency in the activity of uroporphyrinogen decarboxylase, causing the buildup of excess uroporphyrinogen.
- Hydroxymethyl bilane is a major anabolic product, from the biosynthetic reaction of porphobilinogen ( PBG ) and uroporphyrinogen I synthase ( known as porphobilinogen deaminase ).
- In the metabolism of porphyrin, it is formed from uroporphyrinogen III by the enzyme uroporphyrinogen III decarboxylase, and it is converted into protoporphyrinogen IX by coproporphyrinogen III oxidase.
- In the metabolism of porphyrin, it is formed from uroporphyrinogen III by the enzyme uroporphyrinogen III decarboxylase, and it is converted into protoporphyrinogen IX by coproporphyrinogen III oxidase.
- Siroheme is synthesized from the central tetrapyrrole molecule uroporphyrinogen III, which forms the first branch-point of tetrapyrrole biosynthetic pathway, the other branch being the heme / chlorophyll branch.
- Four PBGs are then combined through deamination into hydroxymethyl bilane ( HMB ), which is hydrolysed to form the circular tetrapyrrole uroporphyrinogen III . This molecule undergoes a number of further modifications.
- The primary cause of this disorder is a deficiency of uroporphyrinogen decarboxylase ( UROD ), a cytosolic enzyme that is a step in the enzymatic pathway that leads to the synthesis of heme.
- The combination of this increased demand and reduced activity of uroporphyrinogen decarboxylase disrupts heme production and allows byproducts of the process to accumulate in the body, triggering the signs and symptoms of porphyria cutanea tarda.
- Uroporphyrinogen ( urogen ) III methyltransferase ( UMT ) catalyzes a reaction that yields two fluorescent products which produce a red-orange fluorescence in the 590-770 nm range when illuminated with ultraviolet light.
- Four molecules of porphobilinogen combine to form a linear tetrapyrrole, which cyclizes to uroporphyrinogen III . Oxidation and side-chain modifications lead to the synthesis of protoporphyrin IX, which acquires an iron atom to form heme.
- Uroporphyrinogen III decarboxylase ( UroD ) is a homodimeric enzyme (, ) that catalyzes the fifth step in heme biosynthesis : the elimination of carboxyl groups from the four acetate side chains of uroporphyrinogen III to yield coproporphyrinogen III.
- Uroporphyrinogen III decarboxylase ( UroD ) is a homodimeric enzyme (, ) that catalyzes the fifth step in heme biosynthesis : the elimination of carboxyl groups from the four acetate side chains of uroporphyrinogen III to yield coproporphyrinogen III.
- It is thought to do so by causing oxidative damage to liver cells, resulting in oxidized species of uroporphyrinogen that inhibit the activity of hepatic UROD . It is also felt to increase the uptake of iron in liver cells, leading to further oxidation of uroporphyrinogen by the release of activated oxygen species.
- It is thought to do so by causing oxidative damage to liver cells, resulting in oxidized species of uroporphyrinogen that inhibit the activity of hepatic UROD . It is also felt to increase the uptake of iron in liver cells, leading to further oxidation of uroporphyrinogen by the release of activated oxygen species.
- The difference between the two forms, is the arrangements of the four propionic acid ( " P " groups ) and the four acetic acid groups ( " A " groups ), where non-enzyamtically conversion into uroporphyrinogen I results in an AP-AP-AP-AP symmetry, whereas the enzymatically conversion into uroporphyrinogen III lead to a reversed AP-group and hence an AP-AP-AP-PA arrangement.
- The difference between the two forms, is the arrangements of the four propionic acid ( " P " groups ) and the four acetic acid groups ( " A " groups ), where non-enzyamtically conversion into uroporphyrinogen I results in an AP-AP-AP-AP symmetry, whereas the enzymatically conversion into uroporphyrinogen III lead to a reversed AP-group and hence an AP-AP-AP-PA arrangement.
uroporphyrinogen sentences in Hindi. What are the example sentences for uroporphyrinogen? uroporphyrinogen English meaning, translation, pronunciation, synonyms and example sentences are provided by Hindlish.com.