1. Neuropilin 1 has been implicated in the vascularization and progression of cancers. 2. It is possible, though, that these changes simply reflect vascularization effects. 3. The tumor has a scant stroma and central necrosis because of the poor vascularization . 4. The rich vascularization of the SCO was first reported by Pesonen ( 1940 ). 5. Furthermore, the amount of SOX9 is reduced and defects in vascularization are found. 6. It may also be involved in the broad control of tissue vascularization during development. 7. The cortex has a moderate amount of vascularization . 8. Angiopoietin-2, on the other hand, promotes cell death and disrupts vascularization . 9. In addition, the porous structure allows for soft tissue adherence and vascularization within the implant. 10. The angiogenic switch leads to tumor expression of pro-angiogenic factors and increased tumor vascularization .