1. The absence of a vagina is a result of vaginal agenesis . 2. Born in Missisauga, Ontario, Bowden lives with sacral agenesis . 3. There is a possible correlation between tooth agenesis and innervation. 4. Patients with uterine abnormalities may have associated renal abnormalities including unilateral renal agenesis . 5. Mutations in the gene have been linked with pancreatic agenesis and congenital heart defects. 6. A relationship was also postulated between abnormalities of the brainstem and the presence of agenesis . 7. Two substitution mutations, Arg196Pro and Met61Lys cause only familial non-syndromic tooth agenesis . 8. Affected women have been found to have vaginal agenesis , hypoplastic, or bicornuate uterus. 9. Adults with unilateral renal agenesis have considerably higher chances of hypertension ( high blood pressure ). 10. Depending on the type of sacral agenesis , bowel or urinary bladder deficiencies may be present.