Amyoplasia is characterized by severe joint contractures and muscle weakness.
There have been no reports of recurrent cases of amyoplasia in a family.
Amyoplasia is a sporadic condition that occurs due to lack of fetal movement in the womb.
The fetal akinesia in amyoplasia is thought to be caused by various maternal and fetal abnormalities.
So amyoplasia may also include an intermediate common pathway, rather than the primary cause of the contractors.
Similarly, connective tissue tendon and skeletal defects may contribute to the fetal akinesia and be the primary cause of amyoplasia.
About 10 % of children with amyoplasia have evidence of vascular compromise including bowel atresia, abdominal wall defects, and gastroschisis.
Studies involving amyoplasia have revealed similar findings of the muscle tissue due to various causes including that seen in sacral agenesis and amyotrophic lateral sclerosis.
In that same year, 1986, Dr . Curry was amongst another group of geneticists who discovered and reported the link between amyoplasia ( a devastating condition of nerve cell drop-out ) and bowel atresia and defects of the muscular layer of the trunk.
Children born with one or more joint contractures have abnormal fibrosis of the muscle tissue causing muscle shortening, and therefore are unable to perform active extension and flexion in the affected joint or joints . has been divided into three groups : amyoplasia, distal arthrogryposis, and syndromic.