ganglioside sentence in Hindi
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- The hydrolysis of GM2-ganglioside requires three proteins.
- It may play a role in modulating the ganglioside content of the lipid bilayer.
- In particular, beta-hexosaminidase A breaks down a fatty compound called GM2 ganglioside.
- After several hours, Lord came upon a report about an experimental drug, GM-1 ganglioside.
- The letter G refers to ganglioside, and M is for monosialic acid as it has one sialic acid only.
- The GLB1 protein is a beta-galactosidase that cleaves the terminal beta-galactose from ganglioside substrates and other glycoconjugates.
- Mutations in the beta-chain lead to Sandhoff disease, a lysosomal storage disorder characterised by accumulation of GM2 ganglioside.
- Beginning in 1975, the scientist supported the drug Cronassial ( a particular ganglioside ) produced by Fidia from bovine brain tissue.
- Glutamate acts as a base by deprotonating the water leading to the formation of the product complex and the G M3 ganglioside.
- The disease occurs when harmful quantities of a fatty acid derivative called a ganglioside accumulate in the nerve cells of the brain.
- For the cholera toxin, the principal glycolipid receptor for the cholera toxin is ganglioside GM1 . that is in the endoplasmic reticulum.
- 9-O-acetyl GD3 ganglioside is an acetylated glycolipid which is found in the cell membranes of many types of vertebrate cells.
- For example, fluorophores conjugated to cholera-toxin B-subunit, which binds to the raft constituent ganglioside GM1 is used extensively.
- The name " ganglioside " was first applied by the German scientist Ernst Klenk in 1942 to lipids newly isolated from residues.
- Mutations in the alpha or beta subunit genes lead to an accumulation of GM2 ganglioside in neurons and neurodegenerative disorders termed the GM2 gangliosidoses.
- Mutations in the " HEXB " gene disrupt the activity of these enzymes, preventing the breakdown of GM2 ganglioside and other molecules.
- This drug is a reversible inhibitor of the enzyme glucosylceramide synthase, which catalyzes the �rst step in synthesizing glucose-based glycosphingolipids like GM2 ganglioside.
- In humans the brain has the highest sialic acid concentration, where these acids play an important role in neural transmission and ganglioside structure in synaptogenesis.
- SV40 utilizes two different receptors to bind onto cell surface : ganglioside GM1 located in lipid rafts and major histocompatibility ( MHC ) class I molecule.
- Mutations in this gene may be involved in the development and progression of meningioma through modification of ganglioside composition and other glycosylated molecules in tumor cells.
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