1. The hydrolysis of GM2-ganglioside requires three proteins. 2. It may play a role in modulating the ganglioside content of the lipid bilayer. 3. In particular, beta-hexosaminidase A breaks down a fatty compound called GM2 ganglioside . 4. After several hours, Lord came upon a report about an experimental drug, GM-1 ganglioside . 5. The letter G refers to ganglioside , and M is for monosialic acid as it has one sialic acid only. 6. The GLB1 protein is a beta-galactosidase that cleaves the terminal beta-galactose from ganglioside substrates and other glycoconjugates. 7. Mutations in the beta-chain lead to Sandhoff disease, a lysosomal storage disorder characterised by accumulation of GM2 ganglioside . 8. Beginning in 1975, the scientist supported the drug Cronassial ( a particular ganglioside ) produced by Fidia from bovine brain tissue. 9. Glutamate acts as a base by deprotonating the water leading to the formation of the product complex and the G M3 ganglioside . 10. The disease occurs when harmful quantities of a fatty acid derivative called a ganglioside accumulate in the nerve cells of the brain.
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