This is in response to mild trauma or even spontaneously, such as in joints ( haemarthrosis ) or muscles . Factor IX deficiency can cause interference of the coagulation cascade, thereby causing spontaneous hemorrhage when there is trauma.
Muscle and joint haemorrhages-or haemarthrosis-are indicative of haemophilia, while digestive tract and cerebral haemorrhages are also germane to other coagulation disorders . Though typically not life-threatening, joint bleeding is one of the most serious symptoms of haemophilia.
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